Skip to main content
. 2016 Apr 1;11(4):e0152807. doi: 10.1371/journal.pone.0152807

Fig 6. Rapid signaling through ERα is required for E2-dependent EC proliferation & migration.

Fig 6

(A) Relative cell counts for stable Ctrl, WT or KRR hEC cell lines +/- 10nM E2, normalized to counts +Veh. (B) A “scratch” wound was made with a pipette tip on Control, WT or KRR hECs at near confluence, and the number of cells migrating into the scratch after 48 hours counted. Top: Quantitation of migration data. Bottom: representative images of cells after 48 hr migration. Dotted lines indicate the borders of the scratch at time 0. Data is normalized to +Veh for each cell line. *: different from WT+Veh, p. <0.05, #: different from KRR+E2, p. <0.05.