Table 3.

Cardiovascular and all cause death rate stratified by quartile of age, LVEF, lymphocyte GRK2 and NT-proBNP.

Cardiac Death rate
	Quartile				P
	1st	2nd	3rd	4th
Age	20.6% (26.8%)	27.9% (39.9%)	39.7% (45.9%)	67.1% (54.2%)	≤0.0001
LVEF	66.1% (50.9%)	59.5% (47.5%)	28.0% (42.7%)	23.9% (37.1%)	≤0.0001
GRK2	15.9% (28.3%)	26.6% (39.9%)	59.1% (48.2%)	56.3% (58.0%)	≤0.0001
NT-proBNP	9.23% (20.7%)	23.3% (38.8%)	47.1% (47.7%)	78.1% (58.3%)	≤0.0001

All Cause Death rate
	Quartile				P
	1st	2nd	3rd	4th
Age	30.2% (39.8%)	44.3% (52.2%)	52.4% (57.5%)	74.3% (64.4%)	≤0.0001
LVEF	89.3% (65.4%)	62.2% (60.6%)	37.6% (53.6%)	32.4% (45.0%)	≤0.0001
GRK2	23.8% (39.1%)	34.4% (52.0%)	75.8% (60.5%)	68.8% (69.9%)	≤0.0001
NT-proBNP	21.5% (32.4%)	36.8% (52.1%)	58.8% (60.6%)	85.9% (70.1%)	≤0.0001

Boldface data refer to Cox adjusted cumulative death rate at 60 months. LVEF= left ventricular ejection fraction; GRK2= G protein-coupled receptor kinase 2; NT-proBNP= N terminal pro-Brain Natriuretic Peptide