Table 1.
Baseline characteristics compared across baseline SAI exposure cohorts and stratified by race
| Variables | African American | Non-African American | ||
|---|---|---|---|---|
| Baseline SAI >6 (n=311) | Baseline SAI ≤ 6 (n=313) | Baseline SAI >6 (n=388) | Baseline SAI ≤ 6 (n=159) | |
| Recipient Characteristics | ||||
| Mean Age (±SD) | 53±12 | 48±14* | 55±13 | 46±16* |
| Female Gender | 37% | 48%* | 36% | 47%* |
| History of Diabetes | 42% | 37% | 30% | 24% |
| History of Hypertension | 94% | 95% | 92% | 85%* |
| History of Heart Disease | 14% | 17% | 24% | 17% |
| Preemptive | 14% | 7%* | 38% | 24%* |
| Mean Years on Dialysis (±SD) | 3.2±2.6 | 4.0±3.2* | 1.6±2.0 | 2.2±2.2* |
| Previous Kidney Transplant | 7% | 7% | 11% | 18%* |
| Donor Characteristics | ||||
| Deceased Donor | 90% | 93% | 70% | 80%* |
| Mean Age (±SD) | 38±15 | 33±16* | 39±15 | 34±15* |
| AA Race | 29% | 36% | 14% | 20% |
| Extended Criteria Donor | 15% | 9%* | 18% | 10% |
| Transplant Characteristics | ||||
| Cytolytic Induction | 45% | 46% | 38% | 50%* |
| Mean PRA (±SD) | 15±28 | 19±30 | 14±28 | 24±35* |
| PRA >20% | 23% | 33%* | 21% | 31%* |
| PRA >80% | 8% | 10% | 7% | 16%* |
| Mean HLA MM (±SD) | 4.6±1.3 | 1.6±1.2 | 3.9±1.6 | 3.6±1.7 |
| Mean Cold Time, hrs (±SD) | 17.7±8.9 | 17.7±8.3 | 14±10 | 16±10 |
| Mean Warm Time, min (±SD) | 37±8 | 38±8 | 36±9 | 36±7 |
| Delayed Graft Function | 17% | 19% | 10% | 8% |
*
p<0.05, as compared to the estimate in the same racial cohort