Table 2.
Comparison of clinical and hemodynamic parameters in series of patients with COPD – PH with or without associated disease (left heart disease, thromboembolic disease, obesity hypoventilation or sleep apnoea), HFpEF – PH and PAH
| COPD–PH | HFpEF–PH | PAH | ||
| Without associated disease | With associated disease | |||
| Subjects n | 11 | 16 | 20 | 20 |
| Age years | 67 (63–68) | 61 (56–68) | 71.3±7.8 | 70.2±6.7 |
| BMI kg m−2 | 26 (21–30) | 26 (22–33) | 31±6.8 | 28.2±3.2 |
| Women % | 80 | 70 | ||
| mPAP mmHg | 48 (46–50) | 43 (42–49) | 50.2±7.1 | 50.2±9.5 |
| PAWP mmHg | 6.0 (4.0–7.0) | 9.0 (4.0–18.0) | 22.8±4.4 | 9.6±3.1 |
| RAP mmHg | 7.0 (5.0–9.0) | 5.0 (3.0–9.7) | 14.8±4.9 | 10.7±5.6 |
| TPG mmHg | 27.5±4.8 | 40.5±8.8 | ||
| DPG mmHg | 6.3±6.2 | 22.0±7.8 | ||
| CI L min−1·m−2 | 2.3 (1.8–2.5) | 2.8 (1.9–3.8) | 2.5±0.5 | 2.3±0.3 |
| TPR WU | 21.3 (17.6–26.6) | 14.9 (11.0–28.4) | ||
| PVR WU | 6.3±2.1 | 9.3±2.7 | ||
Data are expressed as mean±sd or median (interquartile range). BMI: body mass index; mPAP: mean pulmonary artery pressure; PAWP: pulmonary artery wedge pressure; RAP: right atrial pressure; TPG: transpulmonary gradient; DPG: diastolic pulmonary gradient; CI: cardiac index; TPR: total pulmonary resistance; PVR: pulmonary vascular resistance. Data from ref 40 and 41.