Figure 1.

Localization of renin and miR-181a in the human kidney by immunohistochemistry and in situ hybridization, respectively. (A–D) Sections through histological compartments of the kidney: (A) glomerulus; JGA, juxtaglomerular apparatus; *, distal convoluted tubule; (B) cortical tubules (arrows indicate distal convoluted tubules); (C) outer medulla; black arrows, collecting ducts; black arrowhead, loop of Henle; white arrows, loop of Henle (thick ascending limb); (D) inner medulla; black arrows, collecting duct; short black arrows, peritubular capillaries; white arrows, loop of Henle; all images in row A, 200×, B, 100×, C, 200× and D, 100×.