Table 2.
Blood gas in animals at baseline and after sea water drowning
| Baseline | 15 min | 60 min | 120 min | 180 min | 240 min | |
|---|---|---|---|---|---|---|
| pH | ||||||
| Control | 7.35 ± 0.03 | 7.23 ± 0.03* | 7.22 ± 0.20* | 7.21 ± 0.12* | 7.18 ± 0.10* | 7.16 ± 0.10* |
| CVVH | 7.37 ± 0.05 | 7.22 ± 0.09* | 7.34 ± 0.08# | 7.34 ± 0.06# | 7.36 ± 0.05# | 7.40 ± 0.08# |
| P a CO 2 (mmHg) | ||||||
| Control | 35.1 ± 1.21 | 35.17 ± 3.67 | 40.48 ± 7.03* | 43.28 ± 5.21* | 40.7 ± 5.14* | 40.68 ± 5.83* |
| CVVH | 34.5 ± 2.32 | 31.53 ± 7.13 | 33.13 ± 8.29 | 37.23 ± 3.18 | 39.33 ± 7.35 | 38.22 ± 8.11 |
| P a O 2 (mmHg) | ||||||
| Control | 102.4 ± 4.03 | 33.5 ± 4.03* | 58.2 ± 11.2* | 61.2 ± 8.67* | 61.8 ± 10.0* | 65.2 ± 7.88* |
| CVVH | 101.0 ± 2.73 | 36.4 ± 8.98* | 61.6 ± 4.93* | 68.1 ± 10.0* | 76.0 ± 5.98* # | 86.5 ± 4.72# |
| AB (mmol/L) | ||||||
| Control | 21.4 ± 3.2 | 15.9 ± 4.0* | 16.1 ± 3.6* | 15.9 ± 3.8* | 15.7 ± 2.6* | 15.7 ± 3.9* |
| CVVH | 22.1 ± 3.7 | 15.6 ± 3.4* | 16.4 ± 4.1* | 18.2 ± 2.4 | 19.9 ± 3.8# | 21.5 ± 2.4# |
| BE (mmol/L) | ||||||
| Control | –4.1 ± 0.9 | –11.2 ± 5.2* | –11.1 ± 2.5* | –11.9 ± 3.8* | –12.3 ± 4.3* | –13.1 ± 3.7* |
| CVVH | –4.8 ± 1.5 | –11.7 ± 3.8* | –9.3 ± 3.2* | –7.1 ± 2.8# | –5.2 ± 1.7# | –4.7 ± 2.9# |
| S a O 2 (%) | ||||||
| Control | 97.5 ± 0.92 | 53.9 ± 7.33* | 75.6 ± 8.75* | 80.9 ± 7.24* | 84.4 ± 6.58* | 86.6 ± 5.98* |
| CVVH | 98.6 ± 0.58 | 50.2 ± 10.95* | 86.6 ± 5.71 | 90.9 ± 4.33# | 92.7 ± 4.62# | 94.9 ± 3.49# |
Blood gas was determined in arterial blood samples from animals before and 15, 50, 120, 180, and 240 minutes after involuntary intratracheal sea water infusion. All animals received mechanical ventilation after sea water infusion and then were randomly divided into control and CRRT group *p < 0.05, vs, the same group of animals before infusion (baseline); #p < 0.05, vs, animals in control group at the same time point