Table 1.
The downregulated DEPs in P6 tubule cells detected by LC-MS (fold change >1.5)
| Accession | Description | Protein | P6/P3 ratio | Standard deviation |
|---|---|---|---|---|
| NP_001074007.2 | aldo keto reductase family 1 member B15 | AKR1B15 | 0.01 | 0.006 |
| NP_001002858.1 | annexin A2 | ANXA2 | 0.12 | 0.025 |
| NP_001619.1 | aldose reductase | AKR1B1 | 0.17 | 0.026 |
| XP_933678.1 | PREDICTED POTE ankyrin domain family member I | POTEI | 0.18 | 0.15 |
| NP_002037.2 | glyceraldehyde 3 phosphate dehydrogenase | GAPDH | 0.30 | 0.03 |
| NP_000289.1 | pyruvate kinase isozymes R L | PKLR | 0.37 | 0.016 |
| NP_003290.1 | endoplasmin precursor | HSP90B1 | 0.41 | 0.006 |
| NP_002256.2 | importin subunit beta 1 | KPNB1 | 0.41 | 0.02 |
| NP_003325.2 | ubiquitin like modifier activating enzyme 1 | UBA1 | 0.43 | 0.007 |
| NP_005339.3 | heat shock protein HSP 90 alpha | HSP90AA2 | 0.44 | 0.004 |
| NP_001153706.1 | sodium potassium transporting ATPase subunit alpha 1 | ATP1A1 | 0.48 | 0.019 |
| NP_001171651.1 | glucose 6 phosphate isomerase | GPI | 0.61 | 0.009 |
| NP_001393.1 | elongation factor 1 alpha 1 | EEF1A1 | 0.66 | 0.009 |
| NP_945189.1 | protein glutamine gamma glutamyltransferase 2 | TGM2 | 0.63 | 0.017 |
| NP_065843.3 | neutral cholesterol ester hydrolase 1 | AADACL1 | P3 | |
| NP_000687.3 | 4 trimethylaminobutyraldehyde dehydrogenase | ALDH9A1 | P3 | |
| NP_004299.1 | rho GTPase activating protein 1 | ARHGAP1 | P3 | |
| NP_001719.2 | basigin precursor | BSG | P3 | |
| NP_001019820.1 | calnexin precursor | CANX | P3 | |
| NP_006575.2 | T complex protein 1 subunit zeta 2 | CCT6B | P3 | |
| NP_002942.2 | dolichyl diphosphooligosaccharide protein glycosyltransferase subunit 2 precursor | DDOST | P3 | |
| NP_004721.1 | eukaryotic peptide chain release factor subunit 1 | ETF1 | P3 | |
| NP_110416.1 | minor histocompatibility antigen H13 | HM13 | P3 | |
| NP_006380.1 | hypoxia up regulated protein 1 precursor | HYOU1 | P3 | |
| NP_005557.1 | L lactate dehydrogenase A chain | LDHA | P3 | |
| NP_001244303.1 | lamin | LMNA | P3 | |
| NP_000894.1 | NADPH dehydrogenase quinone 1 | NQO1 | P3 | |
| NP_005023.2 | plastin 3 | PLS3 | P3 | |
| NP_006397.1 | peroxiredoxin 4 precursor | PRDX4 | P3 | |
| NP_001096137.1 | proteasome subunit alpha type 4 | PSMA4 | P3 | |
| NP_653263.2 | proteasome subunit alpha type 7 like | PSMA7 | P3 | |
| NP_055205.2 | staphylococcal nuclease domain containing protein 1 | SND1 | P3 | |
| NP_110437.2 | thioredoxin domain containing protein 5 precursor | TXNDC5 | P3 | |
| NP_066964.1 | X ray repair cross complementing protein 5 | XRCC5 | P3 |