Table 1.
Number of basophils (gated as SSClow/CD123+/HLA-DR− cells) and expression of CD123 on the surface of basophils (gated as SSClow/CD203c+ cells) as measured by MFI of CD123-FITC in different stimulation conditions
| Stimulant | n | Pre-stimulation | Post-stimulation | p value |
|---|---|---|---|---|
| Number of basophils | ||||
| fMLP | 116 | 1722 (1226, 2184) | 1572 (1037, 2100) | 0.012 |
| Anti-IgE | 104 | 1722 (1221, 2191) | 1414 (972, 1995) | 0.005 |
| Peanut extract | 42 | 1732 (1212, 2174) | 1514 (914, 2041) | 0.134 |
| MFI of CD123-FITC | ||||
| fMLP | 116 | 1082 (98, 1549) | 514 (75, 1020) | <0.001 |
| Anti-IgE | 104 | 1081 (95, 1549) | 495 (60, 1111) | <0.001 |
| Peanut extract | 42 | 1172 (80–2058) | 293 (40, 1244) | <0.001 |
Median (inter-quartile range) is represented. p value refers to the comparison of post-stimulation conditions with the negative control