Table 1.
Correlation between Phased An/Tn Cluster (PATC) content and preference for interaction with chromosome arms
| Correlations for arms regions ONLY | chrI | chrII | chrIII | chrIV | chrV | chrX |
|---|---|---|---|---|---|---|
| log2(arms/centers) vs. PATCs 25KB Pearson R values | 0.38 | 0.37 | 0.17 | 0.44 | 0.26 | 0.51 |
| log2(arms/centers) vs. PATCs 25KB Spearman R values | 0.36 | 0.50 | 0.18 | 0.45 | 0.48 | 0.49 |
| log2(arms/centers) vs. PATCs 50KB Pearson R values | 0.50 | 0.58 | 0.25 | 0.54 | 0.30 | 0.63 |
| log2(arms/centers) vs. PATCs 50KB Spearman R values | 0.46 | 0.60 | 0.25 | 0.55 | 0.58 | 0.61 |
To measure correlation of inter-chromosomal contacts between chromosomal arms regions (defined according to [20]) and PATC enrichment we divided the genome into 25KB (50KB) non-overlapping intervals. For each interval we measured the enrichment for PATC by counting the number of locations with high PATC score (defined as regions with a score of >55 using the algorithm of [29]). In order to measure the level of enrichment of inter-chromosomal arm-arm contacts over the arm-centers contacts we calculate the number of inter-chromosomal arm-arm contacts and number of inter-chromosomal arm-center contacts for every interval. Log2 value of the enrichment for inter-chromosomal arm-arm contacts is used to calculate correlation with PATC enrichment in different genomic regions