Appendix Table 4.
Example of a patient rated “improved” by the experts. Predicted probability of improving is 0.60 according to CRISS.
| Baseline | Follow-up | Absolute change | |
|---|---|---|---|
| Age | 64.65 years | ||
| Disease duration (months) | 30.74 | ||
| Global assessments | |||
| Patient global assessment (0–10)* | 1 | 0 | −1 |
| Physician global assessment (0–10)* | 7 | 4 | −3 |
| Musculoskeletal | |||
| HAQ-DI (0–3)* | 0.375 | 0.250 | −0.125 |
| Tendon friction rubs* | No | No | No change |
| Skin | |||
| MRSS (0–51)* | 21 | 15 | −6 |
| Patient skin interference last month | 8 | 5 | −3 |
| Lung | |||
| FVC% predicted* | 86 | 81 | −5 |
| Breathing VAS (0–10) | 0 | 0 | 0 |
| Renal | |||
| Renal crisis** | Yes | Yes | No change |
| Gastrointestinal | |||
| GI VAS (0–10) | 0 | 0 | 0 |
| Body Mass Index (BMI) | 25.12 | 24.82 | −0.3 |
| Raynaud’s | |||
| Raynaud’s VAS (0–10) | 3 | 4 | 1 |
| Digital ulcers | |||
| Digital ulcers VAS (0–10) | 0 | 8 | 8 |
| Number of digital ulcers | 0 | 0 | 0 |
| HRQOL | |||
| Pain VAS (0–10) | 0 | 2 | 2 |
| Fatigue (SF-36 Vitality scale) (0–100) | 35.12 | 35.12 | 0.0 |
*
included in Step 2;
**
included in Step 1
HAQ-DI= health assessment questionnaire-disability index, MRSS= modified Rodnan skin score, FVC= Forced vital capacity, GI= gastrointestinal, VAS= visual analog scale