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. Author manuscript; available in PMC: 2016 Apr 2.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Jun 7;22(15):5104–5107. doi: 10.1016/j.bmcl.2012.05.099

Scheme 1.

Scheme 1

Synthesis and radiosynthesis of (R)-FEPAQ and (R)-[18F]FEPAQ. Reagents and conditions: (i) (Ts)2O, THF, 6 h; (ii) POCl3, CH2Cl2; (iii) K2CO3, THF; (iv) 4, K2CO3, THF; (v) TFA, CH2Cl2; (vi) fluoroethyl bromide/[18F]FEOTs, DMSO.