Figure 5. Ca²⁺ permeability is similar for GluK2 and GluK2/GluK5 kainate receptors .

A, example membrane currents for GluK2 (left, patch 120507p1) and GluK2/GluK5 (right, patch 120522p2) evoked by 1 ms l‐Glu applications (1 mm, in 150 mm NaCl) at various holding potentials (−100 to +100 mV, 20 mV increments) in the absence of internal polyamines. B, example membrane currents for GluK2 (left, same patch as in A) and GluK2/GluK5 (right, same patch as in A) evoked by 1 ms l‐Glu applications (1 mm, in 30 mm CaCl₂) at various holding potentials (−100 to +100 mV, 20 mV increments) in the absence of internal polyamines. C, I–V relationships for GluK2 (black, n = 4) and GluK2/GluK5 (cyan, n = 8) in 150 mm NaCl external solution. D, I–V relationships for GluK2 (black, n = 5) and GluK2/GluK5 (cyan, n = 3) in 30 mm CaCl₂ external solution. Current values are normalized to the current at −100 mV. E and F, reversal potentials in 150 mm NaCl and 30 mm CaCl₂ external solutions for GluK2 (E) and GluK2/GluK5 (F). All data are represented as mean ± SEM.