Table 1.
Baseline demographic, comorbidity, CRS and olfactory metrics of all patients (n=121)
| Demographics: | Mean [SD] | [RANGE] | N (%) |
|---|---|---|---|
| Age (years) | 47.9 [17.2] | [18 – 80] | |
| Males | 61 (50%) | ||
| White/caucasian | 109 (90%) | ||
| African American | 10 (8%) | ||
| Asian | 1 (1%) | ||
| Hispanic/Latino | 1 (1%) | ||
| Comorbid conditions: | |||
| Asthma | 52 (43%) | ||
| Allergy (testing confirmed) | 80 (66%) | ||
| AERD | 14 (12%) | ||
| Diabetes mellitus (Type I or II) | 10 (8%) | ||
| Depression | 23 (19%) | ||
| Obstructive sleep apnea | 15 (12%) | ||
| Ciliary dyskinesia | 3 (3%) | ||
| GERD | 37 (31%) | ||
| Current tobacco use | 8 (7%) | ||
| Disease characteristics: | |||
| Nasal polyposis | 51 (42%) | ||
| Prior sinus surgery | 69 (57%) | ||
| Septal deviation | 30 (25%) | ||
| Turbinate hypertrophy | 17 (14%) | ||
| Corticosteroid dependency | 17 (14%) | ||
| Disease severity: | |||
| SNOT-22 total score | 56.8 [20.3] | [6 – 102] | |
| RSDI total score | 51.1 [24.1] | [2 – 111] | |
| Computed tomography score | 12.9 [6.3] | [1 – 24] | |
| Endoscopy score | 5.9 [3.2] | [0 – 20] | |
| Olfactory function measures: | |||
| QOD-NS score | 35.2 [13.3] | [0 – 51] | |
| SIT-40 score | 26.4 [10.3] | [0 – 38] | |
| SNOT-22 Q#21 | 3.0 [1.8] | [0 – 5] | |
| RSDI physical subdomain Q#7 | 2.0 [1.4] | [0 – 4] |
SD, standard deviation; AERD, aspirin exacerbated respiratory disease; GERD, gastroesophageal reflux disease; SNOT-22, 22-item SinoNasal Outcome Test; RSDI, Rhinosinusitis Disability Index; QOD, Questionnaire for Olfactory Disorders; NS, negative statements; SIT-40, Smell Identification Test-40; Q, question item