Table 4.
Characteristics of active cancer patients diagnosed with cryptogenic stroke and known stroke mechanisms
| Patient characteristics | Cryptogenic stroke (n = 68) | Known stroke mechanisms (n = 77) | P Value |
|---|---|---|---|
| Age, years | 67 (60–75) | 74 (67–79) | <0.001 |
| Women, % | 46 | 30 | 0.06 |
| Body mass index, kg/m2 | 19.7 (16.9–22.4) | 22.1 (19.6–24.1) | 0.002 |
| Atherosclerotic risk factors, n | 1 (0–2) | 2 (1–3) | <0.001 |
| Hypertension, % | 35 | 74 | <0.001 |
| Hyperlipidemia, % | 37 | 42 | 0.56 |
| Diabetes mellitus, % | 19 | 34 | 0.04 |
| Current smoking, % | 15 | 21 | 0.34 |
| Past stroke, % | 18 | 25 | 0.30 |
| Laboratory findings | |||
| White blood cells, /μL | 7,565 (4,985–10,738) | 6,750 (5,110–9,305) | 0.56 |
| Total lymphocytes, /μL | 904 (585–1270) | 1,149 (777–1,547) | 0.02 |
| Hemoglobin, g/dL | 10.6 (8.4–12.1) | 11.4 (10.1–13.1) | 0.008 |
| Platelets × 104/μL | 14.4 (8.3–22.1) | 19.7 (13.4–25.6) | 0.02 |
| Total cholesterol, mg/dL | 169 (135–205) | 164 (144–189) | 0.78 |
| Albumin, g/dL | 3.2 (2.6–3.6) | 3.4 (2.9–3.8) | 0.07 |
| D‐dimer, μg/mL | 5.1 (2.6–16.2) | 2.6 (0.9–7.6) | <0.001 |
| hsCRP, mg/dL | 1.33 (0.35‐6.80) | 0.72 (0.13‐4.11) | 0.06 |
| CONUT score | 5 (3–8) | 4 (2–7) | 0.02 |
| Imaging findings | |||
| Multiple vascular lesions, % | 71 | 40 | <0.001 |
| Cancer status | |||
| Adenocarcinoma, % | 68 | 59 | 0.29 |
| Systemic metastases, % | 54 | 31 | 0.005 |
| Chemotherapy and/or radiation therapy, % | 40 | 9 | <0.001 |
CONUT, controlling nutritional status; hsCRP, high sensitivity C‐reactive protein.