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. 2016 Mar 23;7(4):236–249. doi: 10.1007/s13238-016-0254-9

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Gene ontology (GO) enrichment analysis of down regulated genes. The filtered significantly down regulated genes (Log2 (fold change) < −2 and P value < 0.05) of each time point were subjected to GO enrichment analysis separately in biological process, molecular biology, and cellular function. (A) Percentage of associated genes/term (%) at 2 h. (B) Percentage of associated genes/term (%) at 2.5 h. (C) Percentage of associated genes/term (%) at 3 h. (D) Percentage of associated genes/term (%) at 3.5 h. The length of bars from each histogram indicates the percentage of associated genes for each term. The number on top of each bar means the number of associated genes