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. 2016 Apr 2;16:45. doi: 10.1186/s12890-016-0205-5

Table 2.

Characteristics of the tumour according to patients’ vital statusa (N = 6,981)

Vital status at
1 month 3 months
Alive Dead Alive Dead
N N = 6,303 N = 678 p-value N = 5,360 N = 1,621 p-value
Histology n = 6,303 n = 678 n = 5,360 n = 1,621
 Small-cell carcinoma, n (%) 961 829 (13.2) 132 (19.5) <0.001 725 (13.5) 236 (14.6) 0.309
 Adenocarcinoma, n (%) 3,221 2,944 (46.7) 277 (40.9) 0.004 2,482 (46.3) 739 (45.6) 0.632
 Squamous-cell carcinoma, n (%) 1,875 1,733 (27.5) 142 (20.9) <0.001 1,488 (27.8) 387 (23.9) 0.002
 Large-cell carcinoma, n (%) 786 665 (10.6) 121 (17.9) <0.001 544 (10.2) 242 (14.9) <0.001
 Adenocarcinoma in situ, n (%) 77 72 (1.1) 5 (0.7) 0.444 67 (1.3) 10 (0.6) 0.045
 Carcinoid tumour, n (%) 40 39 (0.6) 1 (0.2) 0.176 b 38 (0.7) 2 (0.1) 0.011
 Other, n (%) 111 102 (1.6) 9 (1.3) 0.679 86 (1.6) 25 (1.5) 0.095
Genomic mutation n = 6,237 n = 670 n = 5,301 n = 1,606
 Explored, n (%) 2,111 1,969 (31.6) 142 (21.2) <0.001 1,685 (31.8) 426 (26.5) <0.001
If explored, n = 1806 n = 121 n = 1,555 n = 372
 EGFR mutated, n (%) 202 196 (10.9) 6 (5.0) 0.058 179 (11.5) 23 (6.2) 0.003
Stage (7 edition) n = 6,264 n = 672 <0.001 n = 5,334 n = 1,602 <0.001
 Stage ≤ IIB, n (%) 1,129 1,100 (17.6) 29 (4.3) 1,056 (19.8) 73 (4.6)
 Stage IIIA, n (%) 934 905 (14.4) 29 (4.3) 845 (15.8) 89 (5.6)
 Stage IIIB, n (%) 705 643 (10.3) 62 (9.2) 571 (10.7) 134 (8.4)
 Stage IV, n (%) 4,168 3,616 (57.7) 552 (82.1) 2,862 (53.7) 1,306 (81.5)

a1 and 3 months after the diagnosis of primary lung cancer (date of diagnosis = date of histological or cytological sampling);

bFisher test (violation of Chi² test conditions)

N or n: number of subjects

Note: Significant p-value are in bold