Table 3.
Uni- and multivariate Cox regression models of disease-free survival in TNBC patients (N = 57) considering a model of double positivity for TAZ and YAP
| Univariate regression model | Multivariate regression modela | ||||
|---|---|---|---|---|---|
| HR (95 % CI) | p-value | HR (95 % CI) | p-value | ||
| Age | >49 vs ≤49 | 1.17 (0.47–2.88) | 0.738 | ||
| Stage | III vs II | 1.17 (0.44–3.09) | 0.751 | ||
| Grade | III vs I-II | 1.71 (0.65–4.52) | 0.278 | ||
| pCR | no vs yes | 4.36 (1.00–18.99) | 0.050 | 3.81 (0.87–16.71) | 0.076 |
| Ki-67 | ≥60 vs <60 | 0.44 (0.16–1.17) | 0.099 | ||
| TAZ/YAP | TAZpos/YAPpos vs other combinations | 3.44 (1.39–8.48) | 0.007 | 3.07 (1.24–7.61) | 0.016 |
aAdjusted for pCR and TAZ/YAP