Fig. 2.

t-AUCB inhibits cell migration and invasion. a: wound healing analysis for U251 cells treated with vehicle control (DMSO), 10 μM, 100 μM or 200 μM t-AUCB. b: 100 μM or 200 μM t-AUCB treatment suppresses the scratched cell monolayer healing (**P < 0.01), whereas 10 μM t-AUCB has no effect (^# P > 0.05). c, d: matrigel-coated transwell chambers for cell invasion analysis, U87 cells were planted into the chambers and treated with vehicle control (DMSO), 10 μM, 100 μM or 200 μM t-AUCB. Cells treated with 100 μM or 200 μM t-AUCB showed a low level of penetration through the membranes compared with those treated with DMSO or 10 μM t-AUCB (**P < 0.01, ^# P > 0.05)