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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Mutat Res Rev Mutat Res. 2015 Dec 2;767:77–91. doi: 10.1016/j.mrrev.2015.11.001

Figure 2. Dose-response for endogenous and exogenous methylating adducts.

Figure 2

Endogenous (unlabeled) and exogenous (D3-labelled) N7-MeG and O6-MeG were measured after treatment with D3-MNU in AHH-1 cells (from Sharma et al. [5]). Exogenous N7-MeG adducts did not significantly contribute to the total N7-MeG adduct load under low-dose treatment conditions.