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. 2016 Apr 3;16:48. doi: 10.1186/s12887-016-0579-9

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© Selistre et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Proportion of cases of extraocular disease at diagnosis in patients with unilateral and bilateral Rb from 1983 to 2012. Legend: At the point where the two lines meet (between 1993 and 1997), 33 % refers to unilateral cases and 31 % refers to bilateral cases. *Line red: bilateral extraocular *Line blue: unilateral extraocular