MB significantly attenuated learning and memory deficits induced by GCI. A-B: Barnes maze task was performed to test the spatial learning ability of the sham, ischemic control, MB-treated animals, as shown by the latency to find the black escape box at day 9 after GCI. C-D: Probe test in the quadrant where the escape box had been on day 10 after cerebral ischemia. The representative tracks in the quadrant zone are shown and data were statistically compared. Data are presented as mean ± SE, n= 11 per group. . * P<0.05 vs. sham control group, †
P<0.05 vs. I/R group.