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A and B: representative trains of evoked spikelets recorded from control, Dravet syndrome (DS), and genetic epilepsy with febrile seizures plus (GEFS+) local neurons (LNs) at 23 and 35°C. Arrow indicates the poststimulus depolarization in GEFS+ LNs at 35°C. C: spikelet frequency plotted as a function of injected current for the LNs shown above. [Modified from Sun et al. 2012 and Schutte et al. 2014 with permission.]
