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. 2016 Apr 4;6:24024. doi: 10.1038/srep24024

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Effects of daf-16 or daf-2 gene mutation on locomotion behavior in nematodes exposed to GO. (b) Effects of daf-16 or daf-2 gene mutation on lifespan in nematodes exposed to GO. (c) Mutations of age-1, akt-1, akt-2, or daf-18 gene affected GO toxicity on locomotion behavior in nematodes. (d) Mutations of age-1, akt-1, akt-2, or daf-18 gene affected GO toxicity on lifespan in nematodes. Locomotion behavior of nematodes was assessed by endpoints of head thrash and body bend. GO exposure concentration was 100 mg/L. Prolonged exposure was performed from L1-larvae to young adults. Bars represent means ± SEM. ^**P < 0.01 vs. control (if not specially indicated).