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. 2016 Apr 4;6:23965. doi: 10.1038/srep23965

Figure 3. RT4v6 an efficient tumorigenic cell line than its parental RT4 cells (RT4P) exhibits lower ROS production but increased sensitivity to BI-D1870.

Figure 3

(a) DCF-DA FACS showing lower ROS production in RT4v6 cells than in RT4P cells in response to serum withdrawal. Note the approximately 10% difference in ROS increased cells (bar graph). (b) DNA fragmentation analysis using PI-FACS in the presence of 10% serum shows that BI-D1870 (5 μM) as single agent induces increased DNA fragmentation in RT4v6 cells compared to RT4P cells. Note the approximate 10% increase in DNA fragmentation.