Table 3.
Genotype | Tarsal joint (mean ± SD) | Stifle joint (mean ± SD) | Hip joint (mean ± SD) | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Original | Flexion | Extension | ROM | Flexion | Extension | ROM | Flexion | Extension | ROM | |
Controls | 150 ± 11.1 | 45.0 ± 8.0 | 153 ± 6.43 | 108 ± 11.0 | 39.3 ± 6.03 | 146 ± 14.0 | 107 ± 11.4 | 58.3 ± 5.51b** | 146 ± 10.4 | 87.7 ± 15.9b* |
GRMD (Mstn +/+ ) | 153 ± 12.0 | 35.0 ± 7.0b* | 158 ± 11.0 | 123 ± 4.04 | 34.0 ± 3.61 | 138 ± 5.0 | 104 ± 7.94 | 63.0 ± 3.61b* | 140 ± 10.8 | 76.7 ± 13.3 |
GRippet (Mstn +/− ) | 147 ± 19.4 | 53.5 ± 7.85a* | 157 ± 12.5 | 104 ± 8.73 | 42.0 ± 5.35 | 140 ± 5.26 | 97.5 ± 6.56 | 77.5 ± 4.93a* | 134 ± 13.3 | 56.5 ± 12.5 |
ROM range of motion
aSignificantly different (*p < 0.05) from GRMD dogs
bSignificantly different (*p < 0.05; **p < 0.01) from GRippets