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Effect of Saikokaryukotsuboreito (SKRBT) on the fertility of aging male mice. Aging males were paired with 2-month-old females for a 60 days continuous breeding study. (a) The latency to the first litter after pairing with the females; (b) The average number of litters in a 60-day period; (c) The average number of pups per litter. *P <s 0.05; n = 10/group.
