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. Author manuscript; available in PMC: 2016 Oct 5.
Published in final edited form as: Angew Chem Int Ed Engl. 2015 Aug 25;54(41):12064–12068. doi: 10.1002/anie.201506346

Figure 2.

Figure 2

Visualization of Cry2-mCh-BaxS184E (a – c) and Cry2-mCh (d – f) light-triggered recruitment to mitochondria in HeLa cells and the attendant cell morphology. Cells are shown prior to illumination (a, d), 2 min (b, e), and 18 min after first light pulse (10 ms pulse every 2 min). Cry2-BaxS184E cells undergo rapid shrinkage (b) and eventual detachment (c; see middle cell), while Cry2-mCh cells maintain an adherent morphology throughout the light course.