(a) HPLC analysis of FPP and GGPP levels in the non-treated LNCaP, 22Rv1, and PC3 cell lines. (b) Representative Western blot analysis of Ras and Rab6 in the non-treated LNCaP, 22Rv1, and PC3 cell lines. The Ras and Rab6 antibodies detect both the unprenylated (aqueous) and prenylated (detergent) forms of Ras and Rab6 respectively, requiring separation by TX-114. Statistical significance indicated as * (P < 0.05), ** (P < 0.005), and *** (P < 0.0005) as determined by Student’s t Test. Error bars indicate standard deviation