Skip to main content
. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neurobiol Dis. 2015 Aug 15;82:466–477. doi: 10.1016/j.nbd.2015.08.008

Figure 6. Detection of p75NTR in immature striatal oligodendrocytes of zQ175 mice.

Figure 6

(A) Scheme showing the expression timeline of different oligodendrocyte markers in different stage of oligodendrocyte development. OPC, oligodendrocyte precursor cells. OL, oligodendrocyte. (B–E) Colocalization of p75NTR labeled cells with oligodendrocyte lineage marker Olig2 (B) and CNPase (D), but not oligodendrocyte precursor cell marker NG2 (C) or mature oligodendrocyte marker CC1 (D) in the striatum of zQ175 homozygous mice at the age of 12 months. (F) p75NTR-immunoreactive cells (arrow) in the striatum do not colocalize with cleaved caspase-3 immunoreactivity (arrowhead). Scale bar, 20μm.