Table-4.
Effect of I. tinctoira ethanolic extract on serum parameters (mean±SE) in sheep naturally infected with GI nematodes.
| Serum parameters | Period | Dose (mg/kg) | Positive control | Negative control | ||
|---|---|---|---|---|---|---|
| 125 | 250 | 500 | ||||
| BUN | 0-day | 49.07±3.50 | 48.77±0.26 | 50.77±1.82 | 43.37±1.78 | 47.23±6.89 |
| 3rd-day | 38.90±1.85 | 38.93±1.10 | 50.70±3.00 | 52.90±2.25 | 42.47±11.11 | |
| 12th-day | 48.17±5.74 | 48.70±1.46 | 49.33±2.03 | 47.10±1.46 | 49.43±1.15 | |
| Overall | 45.38abcd±2.59 | 45.47abcd±1.72 | 50.27ab±1.19 | 47.79abcd±1.67 | 46.38abcd±3.93 | |
| Serum creatinine | 0-day | 1.47±0.12 | 1.37±0.03 | 1.53±0.03 | 1.40±0.06 | 1.40±0.12 |
| 3rd-day | 1.30±0.00 | 1.33±0.03 | 1.47±0.07 | 1.53±0.09 | 1.57±0.09 | |
| 12th-day | 1.50±0.12 | 1.47±0.03 | 1.53±0.03 | 1.43±0.03 | 1.47±0.03 | |
| Overall | 1.42bc±0.06 | 1.39bc±0.03 | 1.51abc±0.03 | 1.46bc±0.04 | 1.48bc±0.05 | |
| SGOT | 0-day | 115.83±2.89 | 103.23±2.57 | 135.13±10.87 | 124.67±2.11 | 109.20±12.01 |
| 3rd-day | 106.67±8.70 | 115.67±14.28 | 125.43±7.97 | 103.97±3.98 | 97.53±12.16 | |
| 12th-day | 121.63±7.86 | 96.77±5.62 | 116.70±9.50 | 113.47±17.02 | 90.27±5.49 | |
| Overall (NS) | 114.71±4.11 | 105.22±5.28 | 125.76±5.45 | 114.03±5.90 | 99.00±5.87 | |
| SGPT | 0-day | 29.00±2.30 | 20.90±4.08 | 13.40±3.38 | 27.83±5.98 | 20.70±1.88 |
| 3rd-day | 24.40±3.92 | 30.00±3.25 | 23.03±6.93 | 23.40±3.80 | 18.90±3.09 | |
| 12th-day | 18.13±2.10 | 21.70±2.15 | 20.97±0.45 | 21.10±1.00 | 17.00±0.61 | |
| Overall (NS) | 23.84±2.14 | 24.20±2.18 | 19.13±2.67 | 24.11±2.29 | 18.87±1.19 | |
Values sharing any one common superscript in a row (overall) do not differ significantly (p<0.01). NS=Not significant (p<0.05), SGPT=Serum glutamic pyruvic transaminase, SGOT=Serum glutamicoxaloacetic transaminase, BUN=Blood urea nitrogen, I. tinctoria=Indigofera tinctoria, GI=Gastrointestinal, SE=Standard error