Figure 8. The effects of chebulagic acid (CA) on vascular endothelial growth factorA (VEGFA) induced new blood formation or angiogenesis in the CAM assay.
(a, f) Phosphate buffered saline (PBS) used as control did not induce blood vessel formation. (b, f) On the contrary, VEGFA stimulated new blood vessel formation. (c, f) 1 μM of CA did not inhibit VEGFA induced angiogenesis. (d, e, f) 2 or 5 μM of CA inhibited VEGFA induced new blood vessel formation. The photograph represents six separate experiments.