Table 1.
MicroRNA | Target genes | Type of ocular neovascularization | References |
---|---|---|---|
MiR-126 | VEGF, HIF-1a, IGF | RNV, CNV | [65–68] |
MiR-200b | VEGF, OXR1 | RNV | [69, 70] |
MiR-31 | PDGF-B, HIF-1α | RNV, CNV | [72] |
MiR-150 | VEGF, PDGF-B | RNV, CNV | [72] |
MiR-184 | Fzd4 | RNV, CNV | [72] |
MiR-132 | Ras-GAP | CV | [71] |
MiR microRNA, HIF-1α hypoxia-inducible factor-1α, IGF insulin-like growth factor, OXR1 oxidation resistance 1, PDGF-B platelet-derived growth factor-B, Fzd4 Frizzled4, Ras-GAP Ras-glyceraldehyde-3-phosphate, RNV retinal neovascularization, CNV choroidal neovascularization, CV corneal neovascularization