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. 2016 Mar 11;156:361–370. doi: 10.1007/s10549-016-3734-y

Table 3.

Relative survival

N of observed deaths/N of expected deaths Relative survival at 10 years (%) RER 95 % CI p** RER* 95 % CI p**
Lower Upper Lower Upper
HER2
 Negative: 0/1+ 712/536 84 1 (Reference) 1 (Reference) 
 2+ 135/105 88 0.91 0.46 1.82 0.796 0.78 0.45 1.35 0.373
 3+ 69/22 48 4.75 3.10 7.28 <0.001 2.07 1.26 3.39 0.004
PIK3CA
 Negative 344/250 82 1 (Reference) 1 (Reference) 
 Positive 149/105 81 0.94 0.50 1.76 0.855 1.24 0.78 2.01 0.194

* Adjusted for age, morphology, grade, hormone receptor status, tumour stage, type of breast surgery, type of axillary surgery, radiotherapy, endocrine therapy, chemotherapy

** p values in bold font indicate a statistically significant difference between the groups at the p level of <0.05