Table 2. Selected apparent second order rate constants for reaction of HO• with biological macromolecules and antioxidants.
Target | Apparent second order rate constant (M−1·s−1) |
---|---|
DNA | 8×108 |
RNA | 1×109 |
Hyaluronan | 7×108 |
Linoleic acid | 9×109 |
Collagen | 4×1011 |
Albumin | 8×1010 |
Ascorbate | 1×1010 |
GSH | 1.4×1010 |
Trolox C (water-soluble analogue of α-tocopherol) | 6.9×109 |