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(A) Study A (tofacitinib-naive patients) pneumococcal serotype-specific titre geometric mean fold rise (GMFR) from vaccination baseline and 95% CI at 35 days after vaccination, by exposure subgroup. (B) Study A (tofacitinib-naive patients) influenza antibody (haemagglutination inhibition) titre GMFR and 95% CI 35 days after vaccination, by exposure subgroup. BID, twice daily; DMARD, disease-modifying antirheumatic drug; GMFR, geometric mean fold rise; MTX, methotrexate.
