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Sox21 Depletion with Three Individual siRNAs Biases Cells toward an Extra-Embryonic Cell Fate, Related to Figure 4
(A) Confocal images of control (n = 24) and Sox21 siRNA 1 (n = 12), Sox21 siRNA 2 (n = 14) and Sox21 siRNA 3 (n = 18) siRNA embryos. Sox17 (PE) and Cdx2 (TE) were used as cell lineage markers. Dotted lines mark the ICM.
(B) Contribution of Sox21 siRNA 1,2 and 3 injected cells to TE, PE and EPI, relative to control siRNA cells.
