Table 2.

Pulmonary cytokine concentrations in untreated and microbiota-depleted mice with and without faecal microbiota transplantation during pneumococcal pneumonia

	Untreated	Microbiota depleted	Faeces transplant
TNF-α	878.5 (588.5–1185)	552.9 (476.8–764.2)*	858.9 (660.4–1564)
IL-1	122 (61.59–166.8)	232.5 (143.5–342.1)*	217 (129–307.1)*
IL-6	198.9 (95.72–240.2)	419.4 (279.2–555.6)**	326.8 (210.8–454.7)*
IL-10	227.7 (160–300.3)	123.7 (116.8–128.1)*	174.4 (153.7–189)
CXCL1	144.6 (84.43–223.7)	384.4 (260.3–533.9)***	242.9 (185.4–271)*

Data are expressed as median (IQR) of n=8 mice per group per time point. Measurements are expressed in pg/mL.

*p<0.05 for Untreated versus Microbiota depleted or for Untreated versus Faeces transplant mice (Mann–Whitney U test).

**p<0.01 for Untreated versus Microbiota depleted or for Untreated versus Faeces transplant mice (Mann–Whitney U test).

***p<0.001 for Untreated versus Microbiota depleted or for Untreated versus Faeces transplant mice (Mann–Whitney U test).

CXCL1, (C-X-C motif) ligand 1; IL, interleukin; TNF-α, a tumour necrosis factor-α.