Table 1.
Compound | Cell type | Effect on ROS | Cellular effect | Reference |
---|---|---|---|---|
Metformin | Renal tubular cells, fatty liver cells | Decrease | Anti-apoptotic | 13, 15 |
Metformin | Pancreatic cancer cells | Decrease | Apoptotic | 16 |
Quercetin | Hepatoma, leukemia | Increase | Apoptotic | 24, 25 |
Quercetin | HUVEC cells | Decrease | Anti-apoptotic | 26 |
Curcumin | Renal, skin, fibroblast, lung adenocarcinoma | Decrease | Anti-apoptotic | 3, 30, 31, 32 |
Curcumin | Neuroblastoma | Increase | Apoptotic | 33 |
Vitamin C | WISH | Decrease | Anti-apoptotic | 36 |
Vitamin C | B16 murine cells | Increase | Apoptotic | 38 |
Spirafolide | Neuroblastoma | Decrease | Anti-apoptotic | 39 |
Retinoic acid | Neuron, cardiomyocyte | Decrease | Anti-apoptotic | 41, 42 |
Retinoic acid | HL60 cells | Increase | Apoptotic | 44 |
Dihydromyricetin | Hepatocarcinoma | Decrease | Apoptotic | 45, 46 |
Dihydromyricetin | Lymphocytes, PC12 | Decrease | Anti-apoptotic | 47, 48 |
ROS, reactive oxygen species.