Table 2.
The upper row gives the mean and standard deviation of all white matter microstructural indices for each of the three portions of the fornix in the Healthy ageing cohort. The lower row provides the Pearson r correlation coefficients between the tract-specific microstructural measures and age in the same cohort. Asterisks indicate significant correlations following Bonferroni adjustment (p ≤ 0.0014). Abbreviations: abFornix, anterior part of the body of the fornix; FA, fractional anisotropy; HA, hindrance modulated orientational anisotropy (HMOA); RD, radial diffusivity; MD, mean diffusivity; AD, axial diffusivity; f, tissue volume fraction. Index score = mean (standard deviation). Units for RD, MD and AD scores are given as × 103 mm2 s− 1.
| Healthy ageing cohort (n = 39) | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| abFornix |
Precommissural fornix |
Postcommissural fornix |
||||||||||||||||
| HA | FA | RD | MD | AD | f | HA | FA | RD | MD | AD | f | HA | FA | RD | MD | AD | f | |
| Mean | 0.17 | 0.34 | 1.06 | 1.33 | 1.87 | 0.60 | 0.19 | 0.37 | 1.02 | 1.31 | 1.90 | 0.61 | 0.17 | 0.34 | 1.06 | 1.34 | 1.88 | 0.61 |
| S.D. | 0.03 | 0.02 | 0.11 | 0.13 | 0.18 | 0.04 | 0.04 | 0.03 | 0.10 | 0.12 | 0.17 | 0.05 | 0.04 | 0.04 | 0.12 | 0.14 | 0.21 | 0.04 |
| Age (r) | − 0.25 | − 0.13 | 0.60* | 0.60* | 0.58* | − 0.16 | − 0.20 | − 0.25 | 0.48 | 0.46 | 0.40 | − 0.09 | − 0.25 | − 0.16 | 0.62* | 0.60* | 0.52* | − 0.31 |