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. 2015 Oct 9;364:83–94. doi: 10.1007/s00441-015-2293-6

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© The Author(s) 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Neutrophil and macrophage influx in full-thickness wounds. Immune cells were detected with immunohistochemistry and scored blinded upon grades of influx from 0 (none) to 5 (massive influx). a Neutrophils were stained with an antibody directed against myeloperoxidase (MPO). Increased neutrophil scores were observed in wounds transplanted with NVM+hFF compared to Acell-NVM (&, ˥), NVM+pFF (‡, Ø) and NVM+AF ($, *) (days 7 and 14). b Influx of macrophages (antibody MAC 2.48) in wounds was scored per treatment for post-surgery day 7 and 14. NVM+hFF induced the macrophage influx in the wound area compared to Acell-NVM (&, ˥, days 7 and 14) and NVM+AF (*, day 14). Statistical significance indicated by symbols (Mann–Whitney U test, p < 0.05)