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. 2015 Oct 9;364:83–94. doi: 10.1007/s00441-015-2293-6

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© The Author(s) 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Influx of CD4⁺ and CD8⁺ lymphocytes in full-thickness wounds. The influx of CD4⁺ and CD8⁺ lymphocytes in the wounds was scored blinded for each treatment group (on a scale of 0 (none) to 5 (massive influx)). a Score of CD4⁺ lymphocyte influx in the wound area. A statistically significant higher influx of CD4⁺ lymphocyte was observed in wounds transplanted with NVM+hFF compared to Acell-NVM (&, ˥), and NVM+AF ($, *) (days 7 and 14). b Influx scores of CD8⁺ lymphocytes infiltrated into the wound area. Higher influx of CD8⁺ lymphocytes was observed in wounds treated with NVM+hFF or NVM+pFF in comparison to Acell-NVM (vs. hFF: &, ˥; vs. pFF: <) and NVM+AF (vs. hFF:$, *; vs. pFF: #). Statistical significance is indicated with symbols (Mann–Whitney U test, p < 0.05)