Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Concept of synthetic lethality. Loss-of-function of the essential gene x leads to immediate cell death (A), while loss-of-function of either gene A or gene B does not have a phenotypic effect. In contrast, combined loss-of-function of gene A and B results in a synthetic lethal interaction.
