Table 3.
Sex differences in parameters relating to cortisol timing, production and excretion.
| Males (n = 14) | Females (n = 14) | p value | |
|---|---|---|---|
| 32-hr cortisol AUC (mmol/L.h) | 7340 ± 368 | 13581 ± 1313 | 0.0001* |
| Cortisol amplitude (mmol/L) | 161.8 ± 15.9 | 241.7 ± 23.1 | 0.019a* |
| Cortisol acrophase (dec.h) | 10.04 ± 0.23 | 9.51 ± 0.23 | 0.079a |
| Urinary cortisol acrophase (dec.h) | 9.12 ± 0.32 | 9.04 ± 0.40 | 0.855 |
| 32-hr urinary cortisol excretion (mol) | 519.5 ± 63.8 | 349.2 ± 39.3 | 0.031†* |
| Cortisol clearance (L/kg/h) | 0.92 ± 0.08 | 0.48 ± 0.09 | 0.0008* |
*Significant difference between sexes (p < 0.05). Independent t-tests, † indicates Mann-Whitney test used. Data are mean ± SEM.