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. 2016 Feb 8;23(2):71–79. doi: 10.3109/09286586.2015.1090004

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Published with License by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. The moral rights of the named author(s) have been asserted.

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Figure 2. — Relative risk (RR) of endophthalmitis with aflibercept injections relative to ranibizumab injections in the US; (a) unadjusted, and (b) adjusted results. CI, confidence interval; ER, event rate. Unadjusted results were calculated by Poisson regression. Adjusted results were calculated using the generalized estimating equation model with compound symmetry adjustments; adjustments were made for both injection-level (left/right injection eye, number of prior injections and occurrence of events with prior injections) and patient-level characteristics (age, sex, health plan type and geographical location). *p < 0.05; **p < 0.0001 (χ ² test).