Table 1.

Summary of microarray and proteomic studies in identifying host factors affected during respiratory syncytial virus infection.

Virus strain	Host system	Techniques	No. of host factors identified	Year	Reference
A2	A549	Microarray	306	2001	Zhang et al. [8]
Long	HeLa	Microarray	380	2002	Tian et al. [9]
A2	BALB/c mice	Microarray	411	2007	Janssen et al. [10]
Long	A549	Microarray	377	2007	Martinez et al. [11]
A2	Various cell lines	Microarray	184	2007	Mayer et al. [12]
Circulating strain	Pediatric patients (whole blood)	Microarray	395	2013	Meijas et al. [13]
Circulating strain	Pediatric patients (PBMC)	Microarray	293	2015	Brand et al. [14]
A2	A549	2DE; MALDI-TOF-MS	19	2004	Brasier et al. [15]
A2	A549; Vero	2D-DIGE; LC–MS/MS	22	2012	Hastie et al. [16]
A2	A549	2D-DIGE; MALDI-TOF-MS	34	2010	Jamaluddin et al. [17]
A2	A549	2D-DIGE; LC–MS/MS	14	2010	van Diepen et al. [18]
A2	A549 (SILAC)	SDS-PAGE; LC–MS/MS	431	2010	Munday et al. [19]
Subgroup B	A549 (SILAC)	SDS-PAGE; LC–MS/MS	112	2010	Munday et al. [20]
A2	HEp2	In-solution IEF; LC–MS/MS	69	2011	Ternette et al. [21]
A2	A549	In-solution IEF; LC–MS/MS	146	2014	Dave et al. [22]
Recombinant vaccine (F,G)	BALB/c mice	SDS-PAGE; LC–MS/MS	48	2015	van Diepen et al. [23]

PBMC: peripheral blood mononuclear cell; SILAC: stable isotope labeling with amino acids in cell culture; 2DE: two-dimensional gel electrophoresis; 2D-DIGE: two-dimensional differential gel electrophoresis; SDS-PAGE: sodium dodecyl sulfate-polyacrylamide gel electrophoresis; IEF: isoelectric focusing; MALDI-TOF-MS: matrix-assisted laser desorption ionization-time of flight-mass spectrometry; LC–MS/MS: liquid chromatography–tandem mass spectrometry