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. 2015 Dec 18;20(8):590–596. doi: 10.3109/1354750X.2015.1130190

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© 2016 The Author(s). Published by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/Licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — OCT-based articular surface evaluation. Topographical reconstruction of human articular cartilage ex vivo (A). The volumetric dataset to reconstruct this 8 × 8 mm macroscopically only slightly degraded, Outerbridge grade 1, specimen from the medial femoral condyle in 3D consists of 100 adjacent 2D OCT images. Note the essentially smooth articular surface around a focal lesion (arrow). Individual, in silico sliced 2D cross-sectional OCT images from this dataset representing 1 mm intervals (B, front-to-back). Smooth surfaces of early sections (B1 through B5) matching the first half of the in silico reconstructed tissue (A). Large, surfacing clefts (arrows; B6, B7) and a smaller sub-surface cleft (B8) corresponding to (peri-)lesional cartilage damage in A.