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. 2016 Apr 30;22(2):248–253. doi: 10.5056/jnm15140

Table 4.

Difference in Gastrointestinal Symptoms Between Males with and Without Endoscopic Reflux Esophagitis as Evaluated by the Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease

RE (+) (n = 28) RE (−) (n = 163) OR P-value 95% CI
Heartburn 5 (17.6%) 19 (11.7%) 1.64 0.362 0.56–4.85
Stomach get bloated 5 (17.6%) 21 (12.9%) 1.47 0.479 0.50–4.29
Stomach feel heavy after meals 5 (17.6%) 31 (19.0%) 0.93 0.885 0.33–2.63
Subconsciously rub your chest with your hand 2 (7.1%) 6 (3.7%) 2.01 0.399 0.39–10.52
Feel sick after meals 2 (7.1%) 17 (11.6%) 0.66 0.592 0.14–3.03
Heartburn after meals 2 (7.1%) 14 (8.6%) 0.82 0.799 0.18–3.82
Unusual sensation in your throat 2 (7.1%) 5 (3.1%) 2.43 0.290 0.45–13.19
Feel full while eating meals 2 (7.1%) 12 (7.4%) 0.97 0.967 0.21–4.58
Get stuck when you swallow 1 (3.6%) 4 (2.6%) 1.47 0.733 0.16–13.68
Bitter liquid coming up into your throat 5 (17.6%) 13 (8.0%) 2.51 0.099 0.82–7.70
Burp a lot 9 (32.1%) 22 (13.5%) 3.04 0.014 1.22–7.55
Heartburn if you bend over 0 (0%) 1 (0.6%) 0 0.679 0.98–1.01
Positive of any gastrointestinal symptoms in FSSG 16 (57.1%) 69 (42.3%) 1.82 0.145 0.81–4.09

RE, reflux esophagitis; FSSG, frequency scale for the symptoms of gastroesophageal reflux disease.

A positive symptom was defined as a symptom for which the subject evaluated the frequency with a score of ≥ 2 (sometimes, often, or always).