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Changes from baseline in (A) glycosylated hemoglobin (HbA1c), (B) fasting plasma glucose (FPG), (C) body weight, (D) systolic blood pressure (SBP), and (E) diastolic blood pressure (DBP) in participants younger than 75 and aged 75 and older (efficacy population). LS = least squares; SE = standard error; CI = confidence interval; CANA = canagliflozin. a P < .001 vs placebo (PBO). Statistical testing was not prespecified for post hoc analyses of FPG, body weight, SBP, and DBP.
