Table 3.
The time course of the GCC and cpRNFL thicknesses determined using SD-OCT in patients with NAION.
| Thickness | Initial visit | 1 month | 3 months | 6 months | 12 months | Normal controls | p values |
|---|---|---|---|---|---|---|---|
| GCC thickness (μm) | |||||||
| Total | 96.49 ± 9.14 (0.72%) | 84.28 ± 4.76** (−12.03%) | 74.26 ± 3.30** (−22.49%) | 71.23 ± 5.50** (−25.64%) | 69.51 ± 6.13** (−27.44%) | 95.80 ± 5.75 | 1.000/0.004/0.002/0.002/0.002 |
| Superior | 94.43 ± 7.63 (−1.35%) | 77.03 ± 8.59** (−19.53%) | 67.17 ± 6.12** (−29.84%) | 63.63 ± 5.32** (−33.53%) | 61.03 ± 5.74** (−36.24%) | 95.73 ± 5.97 | 0.993/0.009/0.002/0.002/0.002 |
| Inferior | 98.52 ± 10.86 (2.74%) | 91.35 ± 7.45 (−4.73%) | 81.36 ± 9.47** (−15.16%) | 78.85 ± 11.94** (−17.78%) | 77.99 ± 12.45** (−18.67%) | 95.89 ± 6.28 | 0.999/0.407/0.007/0.004/0.005 |
| GCC parameters (%) | |||||||
| FLV | 1.58 ± 0.72* | 7.25 ± 2.39** | 9.25 ± 2.42** | 10.30 ± 2.16** | 11.17 ± 2.59** | 0.52 ± 0.55 | 0.013/0.002/0.002/0.002/0.002 |
| GLV | 5.73 ± 3.30 | 14.47 ± 2.88** | 22.57 ± 3.71** | 26.89 ± 6.60** | 27.50 ± 6.92** | 4.02 ± 2.76 | 0.760/0.002/0.002/0.005/0.002 |
| cpRNFL thickness (μm) | |||||||
| Total | 190.79 ± 43.47** (78.38%) | 138.26 ± 39.95 (29.27%) | 100.08 ± 37.89 (−6.43%) | 82.96 ± 12.50** (−22.43%) | 79.50 ± 16.30** (−25.67%) | 106.96 ± 7.54 | 0.002/0.165/0.165/0.002/0.002 |
| Superior | 202.20 ± 41.84** (91.24%) | 135.17 ± 55.25 (27.84%) | 93.81 ± 52.00 (−11.27%) | 74.68 ± 14.24** (−29.37%) | 70.21 ± 17.93** (−33.60%) | 106.73 ± 8.17 | 0.002/0.339/0.140/0.003/0.002 |
| Inferior | 179.38 ± 49.75** (65.81%) | 143.71 ± 32.83* (32.84%) | 106.35 ± 26.64 (−1.69%) | 91.24 ± 18.23 (−15.66%) | 88.79 ± 18.36* (−17.93%) | 108.18 ± 8.46 | 0.002/0.034/0.990/0.118/0.018 |
Note. GCC = ganglion cell complex; cpRNFL = circumpapillary retinal nerve fibre layer; SD-OCT = spectral-domain optical coherence tomography; NAION = non-arteritic anterior ischaemic optic neuropathy; FLV = focal loss volume; GLV = global loss volume.
*p < 0.05, **p < 0.01; Steel’s post hoc multiple comparison test.
GCC and cpRNFL thicknesses (%): percentage of increase (positive values) or decrease (negative values) in NAION eyes compared with normal control eyes.