Table 3.
Characteristics of the patients with or without anastomosis and univariate/multivariate logistic regression analysis of risk factors associated with anastomotic leakage (N = 86)
| Factors | AL(+) | AL(−) | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|---|
| All patients | CRT(+) patients | |||||||
| (N = 16) | (N = 70) | Odds ratio | P | Odds ratio | P | Odds ratio | P | |
| Age ≥75 | 3 | 10 | 1.4 | 0.65 | ||||
| Sex (male) | 10 | 53 | 0.53 | 0.29 | ||||
| Diabetes mellitus | 4 | 9 | 2.3 | 0.22 | ||||
| Steroid | 2 | 1 | 9.9 | 0.07 | 3.8 | 0.31 | 3.9 | 0.38 |
| Smoking | 2 | 18 | 0.41 | 0.27 | ||||
| CRT (N = 44) | 12 | 32 | 3.6 | 0.03 | 3.3 | 0.056 | ||
| Albumin on consultation <3.5 g/dL | 3 | 2 | 7.8 | 0.03 | 1.1 | 0.95 | 1.3 | 0.84 |
| Albumin at surgery <3.5 g/dL | 1 | 4 | 1.1 | 0.93 | ||||
| Malnutrition after CRT | 7 | 14 | 1.8 | 0.39 | ||||
| Malnutrition at surgery | 6 | 5 | 5.4 | 0.024 | 6.3 | 0.02 | ||
| ASAPS = 3 | 5 | 9 | 3.1 | 0.08 | 2.8 | 0.17 | 4.6 | 0.14 |
| BMI underweight on consultation | 1 | 7 | 0.6 | 0.8 | ||||
| BMI underweight at surgery | 2 | 7 | 1.3 | 0.49 | ||||
| NRS ≥ 3 on consultation | 3 | 13 | 1.0 | 0.99 | ||||
| NRS ≥ 3 after CRT | 8 | 17 | 1.8 | 0.42 | ||||
| NRS ≥ 3 at surgery | 7 | 16 | 2.6 | 0.1 | ||||
| Blood loss >500 mL | 9 | 28 | 1.9 | 0.24 | ||||
| Operation time >5 h | 8 | 21 | 2.3 | 0.14 | ||||
| AV < 40 mm (N = 29) | 5 | 24 | 0.9 | 0.82 | ||||
| Stage ≥ 2 (N = 52) | 12 | 40 | 2.3 | 0.18 | ||||
AL anastomotic leakage, CRT chemoradiotherapy, BMI body mass index, NRS nutritional risk screening, AV distance from the anal verge, ASAPS American Society of Anesthesiologists Physical Status